* Refers to lens replacement schedule. ** Based on subject selection (or rating or agreement) to statement “The lenses felt comfortable- even when looking at my smart phone or computer screen for an extended period of time” as measured at 16 hours on day 7 for PRECISION7 and day 14 for ACUVUE OASYS 2-week lenses. † Based on in vitro simulated wear for 16 hours a day, measured at end of 7 days with new and advanced techniques using the OCULUS Keratograph 5M. Compared to ACUVUE OASYS 2-Week, Biofinity, and Bausch & Lomb ULTRA. p<0.05. †† Measured at 16 hours. ‡ Measured after lens insertion on Day 7 ^Trademarks are the property of their respective owners. References: 1. In a 2-week prospective clinical study in the US; n=181; p=0.0353; CLEAR CARE Cleaning & Disinfecting Solution used for cleaning and disinfection; Alcon data on file, 2023. 2. Zheng Y, Dou J, Wang Y, et al. Sustained release of a polymeric wetting agent from a silicone-hydrogel contact lens material. ACS Omega. 2022;7(33):29223-29230. doi: 10.1021/ acsomega.2c03310. 3. Global CLI annualized Q3 YTD 2022 including Cosmetic. GfK FY 2022 shares for available countries. GfK $ shares used to approximate CLI sell in DD SiHy DD Non SiHy splits; Alcon data on file, 2022. 4. Dumbleton K, Woods C, Jones L, Fonn D, Sarwer D. Patient and Practitioner Compliance With Silicone Hydrogel and Daily Disposable Lens Replacement in the United States. Eye & Contact Lens 2009;4: 164-171. 5. Based on a survey of 500 US bi-weekly contact lens wearers; Alcon data on file, 2023. 6. Phan CM, Chan VWY, Drolle E, et al. Evaluating the in vitro wettability and coefficient of friction of a novel and contemporary reusable silicone hydrogel contact lens materials using an in vitro blink model. Cont Lens Anterior Eye. 2024. (p<0.05) Based on simulated 7-day daily wear. 7. Alcon data on file, 2022. 8. Based on a survey of 500 US optometrists who fit contact lenses.; Alcon data on file, 2023. Important information for PRECISION7TM (serafilcon A) contact lenses: For daily wear or extended wear up to 6 nights for near/ far-sightedness. Risk of serious eye problems (i.e., corneal ulcer) is greater for extended wear. In rare cases, loss of vision may result. Side effects like discomfort, mild burning or stinging may occur. See instructions for use for wear, care, precautions, warnings, contraindications and adverse effects. The World’s First ACTIV-FLOTM System2 The ACTIV-FLOTM System is a revolutionary 7-day sustained-release technology for outstanding comfort.2,6 It starts with a brand new SiHy material called sera-filcon A. Within this lens, a permanently bound, water-loving moisturizing agent improves the hydrophilicity of the material.2,6 When taken out of the packing solution, a proprietary replenishing agent immediately starts releasing from the core to the surface and continuously moisturizes the lens surface over 7 days.2,6 ACTIV-FLOTM System PRECISION7TM PRECISION7TM: Unique ACTIV-FLOTM System Specially designed for 1-week optimal performance2 + + = New SiHy material serafilcon A Permanently bound, water-loving Moisturizing Agent2,6 Proprietary Replenishing Agent releases from core to surface2,6 JUST PICK YOUR DAY! Fit patients with PRECISION7TM and ask them to... PICK YOUR DAY © 2025 Alcon NORD-PR7-2500001 DR. KATHY DUMBLETON* PhD MCOptom FAAO Dipl AAO FBCLA Clinical Research Scientist and Consultant *Dr. Kathy Dumbleton is a paid Alcon consultant. “One area of study that’s always fascinated me is the possibility of a lens that can elute wetting agents. What’s incredible about PRECISION7TM is the ACTIV-FLOTM System, and what Alcon has accomplished in terms of elution over time. It’s awe-inspiring to scientists like me.” Alcon
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